Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...

DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...

Scope of bimodal methylation: Identification of 325,000 genomic regions—approximately 6% of the genome and 11% of CpG sites—that exhibit a bimodal pattern of fully methylated and fully ...

The basic pattern of genomic DNA methylation is established at the time of embryo implantation through a wave of de novo methylation, but CpG islands are protected through a mechanism that ...

Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies ...

An international team led by UPV/EHU and Biobizkaia reveals the relationship between placental DNA methylation and certain ...

For example, DNA methylation modifies gene expression without altering the nucleotide sequence. A well-studied DNA methylation-based phenomenon is genomic imprinting (ie, genotype-independent ...