Wang and her team were interested in synthesizing different kinds of RNA, which is normally in a linear form with a single polyA tail that is important for protein production. This tail is the ...

The fertilized egg has all the mRNA needed for proteins during rapid cell division. What instructions prevent premature mRNA translation before fertilization? In the 1960s and 1970s, scientists ...

During the oocyte-to-embryo transition (OET), the length of the mRNA poly(A) tail is closely linked to its translational efficiency. Regulation of the poly(A) tail is essential for selective ...

Dr. Vinod Balachandran says mRNA vaccines could stimulate the immune system to recognize and attack pancreatic cancer cells. An experimental approach to treating pancreatic cancer with the messenger ...

The remaining exons are then spliced together, and the spliced mRNA molecule (red) is prepared for export out of the nucleus through addition of an endcap (sphere) and a polyA tail. Once in the ...