The key structural features of tRNA include: The specificity of tRNA-amino acid interactions and the accuracy of codon-anticodon recognition ensure the faithful translation of the genetic code into ...

How does DNA determine an organism’s characteristics? A process called translation decodes RNA created during transcription, and uses it to create proteins that perform specific cellular functions.

When they treated the cultures with synthetic tRNA that carried an easily traceable unconventional amino acid and recognized these rare codons, they found that the TCG triplet introduced the new ...

During tRNA development, the researchers identified 12 highly active tRNA synthetase/tRNA pairs in Escherichia coli that can add canonical and noncanonical amino acids. Then, Badran’s team used ...

Researchers developed a technique to gain a deeper understanding of ribosome function and their cooperative behaviors.

These proteins are made from amino acids, delivered by specialized trucks called transfer RNA (tRNA) to the protein-building ...

Within the ribosome, the mRNA and aminoacyl-tRNA complexes are held together closely, which facilitates base-pairing. The rRNA catalyzes the attachment of each new amino acid to the growing chain.

Wobble base pairing enables a single tRNA molecule to recognize multiple codons for the same amino acid, reducing the number of tRNA molecules required for translation. To ensure accurate translation, ...

In this process, the tRNA molecules work as adapters that proofread the code and, upon a successful match, add the correct amino acids, i.e. the building blocks that make up proteins. For this ...