How does DNA determine an organism’s characteristics? A process called translation decodes RNA created during transcription, and uses it to create proteins that perform specific cellular functions.

The key structural features of tRNA include: The specificity of tRNA-amino acid interactions and the accuracy of codon-anticodon recognition ensure the faithful translation of the genetic code into ...

The research is published in the journal Nucleic Acids Research. The research group created mice lacking the Trmt10a gene and measured tRNA levels in the brain. They discovered a significant ...

When they treated the cultures with synthetic tRNA that carried an easily traceable unconventional amino acid and recognized these rare codons, they found that the TCG triplet introduced the new ...

This codon is almost always AUG, which corresponds to the amino acid methionine. Next, the specific tRNA molecule that carries methionine recognizes this codon and binds to it (Figure 5).

the researchers identified 12 highly active tRNA synthetase/tRNA pairs in Escherichia coli that can add canonical and noncanonical amino acids. Then, Badran’s team used iterative rounds of genetic ...

Wobble base pairing enables a single tRNA molecule to recognize multiple codons for the same amino acid, reducing the number of tRNA molecules required for translation. To ensure accurate translation, ...

In this process, the tRNA molecules work as adapters that proofread the code and, upon a successful match, add the correct amino acids, i.e. the building blocks that make up proteins. For this ...