How does DNA determine an organism’s characteristics? A process called translation decodes RNA created during transcription, and uses it to create proteins that perform specific cellular functions.

One of these hairpin loops contains a sequence called the anticodon, which can recognize and decode an mRNA codon. Each tRNA has its corresponding amino acid attached to its end. When a tRNA ...

The third base of a codon can form non-standard base pairs with the first base of the anticodon, allowing for more flexibility in codon recognition. Wobble base pairing enables a single tRNA molecule ...

Researchers developed a technique to gain a deeper understanding of ribosome function and their cooperative behaviors.

The key structural features of tRNA include: The specificity of tRNA-amino acid interactions and the accuracy of codon-anticodon recognition ensure the faithful translation of the genetic code into ...

the researchers identified 12 highly active tRNA synthetase/tRNA pairs in Escherichia coli that can add canonical and noncanonical amino acids. Then, Badran’s team used iterative rounds of genetic ...

coli tRNA Lys triggered by phage-activation of a latent host-encoded anticodon nuclease PrrC ... element that accounts for guanine nucleotide specificity. Mutations of amino acids that contact the ...

When they treated the cultures with synthetic tRNA that carried an easily traceable unconventional amino acid and recognized these rare codons, they found that the TCG triplet introduced the new ...