Wedemeyer et al, Paracrine FGF21 dynamically modulates mTOR signaling to regulate thymus function across the lifespan, Nature Aging (2025). DOI: 10.1038/s43587-024-00801-1 ...

How your immune system really ages — research shows aging brings adaptation not decline and reveals ways to maintain immune ...

Reference: Wedemeyer SA, Jones NE, Raza IGA, et al. Paracrine FGF21 dynamically modulates mTOR signaling to regulate thymus function across the lifespan. Nat Aging. 2025;5(4):588-606. doi: ...

The findings, published in Nature Aging in February ... increasing FGF21 preserved both the size and function of the thymus, allowing for a broader range of T-cells to develop.

This article delves into the hypothesized mechanisms of Vilon and its prospective roles in various research domains.

The thymus – which produces T cells ... Conversely, poor fitness can accelerate cardiac aging, creating the cardiovascular function of someone decades older. Your kidneys follow one of the ...

His goal is to apply his findings to develop new therapies to promote immunity in cancer patients who receive thymus-­damaging treatments and/or to boost the effectiveness of vaccines in people whose ...

We discovered the function of the thymus and made key findings on the function of the two main subsets of lymphocytes, T cells and B cells. This was the fundamental basis for modern immunology.

Sifting through those factors and understanding how treatments and vaccines could help enhance immune function is a challenge ... As we age, for example, the thymus—a small organ in the chest where ...