The fission yeast cell cycle is controlled by a single CDK, Cdc2, required for both the G1/S and G2/M transitions 14,15.DNA replication and mitosis are triggered by association of Cdc2 with the B ...

The dominant model for eukaryotic cell cycle control proposes that cell cycle progression is driven by a succession of CDK complexes with different substrate specificities. However, in fission ...

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought.

The cell cycle is regulated by cyclins, a type of protein that binds and activates cyclin dependent kinases (CDKs). Skip to content. Menu. Medical Home Life Sciences Home. Become a Member.

Image Credit: Kateryna Kon/Shutterstock.com. Cyclin-dependent kinase inhibitor 1, also known as CDK-interacting protein 1, or more simply as p21, is a cell cycle inhibitor that promotes both CDK ...

Critical parts of the cell cycle machinery are the cyclin-dependent kinases (CDKs), which, when activated, provide a means for the cell to move from one phase of the cell cycle to the next. The CDKs ...

If the cell cycle were like a particular score played by a molecular orchestra, E2F7 was a new conductor, guiding the same instruments in that orchestra to play a new tune, the multiciliation cycle.

Cyclin-dependent kinase enzymes (CDKs) are of two types: cell cycle-regulating CDKs that participate in the progression of the cell cycle and transcriptional ones that control gene expression.

Cell cycle dysregulation in cancer cells represents a clinical option for treating cancer, by using cyclin-dependent kinase 4/6 (CDK4/6) inhibitory agents. Further evaluation on this approach was ...

Cell cycle dysregulation in cancer cells represents a clinical option for treating cancer, by using cyclin-dependent kinase 4/6 (CDK4/6) inhibitory agents. Further evaluation on this approach was ...