Variations in the composition of the extracellular matrix determine properties of the connective tissue. The cells in connective tissue are few and dispersed, so they are not in close contact with ...

The composition of the extracellular matrix differs between tissue types. Though its main function is to provide an essential scaffold for cells, the extracellular matrix also regulates processes ...

Scientists have found a novel way that includes a new lab-grown material that could help slow and even reverse some of the ...

“In this paper, we develop a 3D connective tissue model that enables us to directly quantify how exposing cells in a 3D environment to different nutrients, growth factors or drug treatments results in ...

The findings suggest that connective tissue, and extracellular matrix proteins like lumican, operate outside of cells normally, but as disease or damage break down ECM, get sucked into and ...

During fibrosis, fibroblasts — connective tissue cells that synthesize the extracellular matrix — “become somehow dysregulated, either by injury or by mutation,” he added. “These fibroblast cells ...

A new 3D connective tissue model gives researchers a sophisticated tool to understand the underlying ... there's been a shift in scientific understanding of the extracellular matrix of tissues.

The findings suggest that connective tissue, and extracellular matrix proteins like lumican, operate outside of cells normally, but as disease or damage break down ECM, get sucked into and ...

Led by researchers from NYU Grossman School of Medicine, the work revolves around the extracellular matrix (ECM) of connective tissues, once thought of as an inert framework that shapes bodily ...