Members of this family share common binding partners, including paxillin, PIX, GPCR kinase (GRK) and focal adhesion kinase (FAK) 2. The role of their association with focal adhesion proteins is ...

Kidney International 61, S99–S105 (2002). Parsons, J. T. et al. Focal adhesion kinase: Targeting adhesion signaling pathways for therapeutic intervention. Clinical Cancer Research 14 ...

The table below is a review of notable updates that occurred in January 2025 for investigational products in development.

Even more fascinating is the intricate relationship between lysosomal exocytosis and focal adhesions, structures critical for cell anchoring and communication. By decoding how focal adhesions ...

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor. Oncotarget. 2019, Sep; ...