Scientists with the Fralin Biomedical Research Institute at VTC have created an engineered model of the supportive tissue ...

The conventional way to study lymph node functions is using animal models but this approach suffers from limitations including a lack of relevant immune system to humans, physiological differences ...

Lymph node of a mouse in which lymphatic vessels (green) and tumor exosomes (red) that will direct the early stages of melanoma metastasis are visualized Disclaimer: AAAS and EurekAlert!

(Courtesy: Phys. Med. Biol. 10.1088/1361-6560/ab083a) Researchers have developed a hybrid predictive model to improve the identification of metastatic lymph nodes in individuals with head-and-neck ...

Here we describe a metastatic CRC mouse model and show that liver metastases can manifest without a lymph node metastatic intermediary. Colorectal tumours transplanted onto the colonic mucosa ...

The model's accuracy and precision in predicting lymph node metastasis stages can significantly aid in clinical decision-making and personalized treatment planning. "This is the first model that ...

Metastatic lymph nodes can be the source of distant metastases in mouse models of cancer. ScienceDaily . Retrieved May 30, 2025 from www.sciencedaily.com / releases / 2018 / 03 / 180322140956.htm ...

More information: Looket Dihge et al. Prediction of lymph node metastasis in breast cancer by gene expression and clinicopathological models: Development and validation within a population based ...

In recently published studies, researchers at Lund University and Skåne University Hospital in Sweden have produced new prediction models for improved personalized treatment of lymph nodes in ...

Goals are to generate the lymph node model, validate tissue organization and function, and validate the transport characteristics of drugs. The vision is that this technology can be used for studies ...