Boost for mouse genetic analysis Date: June 22, 2021 ... A genome-wide library of MADM mice for single-cell genetic mosaic analysis. Cell Reports, 2021; 35 (12): 109274 DOI: ...

Luo points out that MADM is more precise than the widely used "knockout mouse" technique, in which a gene of interest is removed ("knocked out") of every cell in the animal's body.

May 1, 2014 (Vol. 34, No. 9) Genetic modification aimed at understanding the function and pathology associated with specific genes is most commonly undertaken in mice, as about 99 percent of human ...

The scientists bred a group of normal mice with a line of genetically modified mice that exhibit behaviors which are the mouse equivalent of autism. The 400 descendants of that crossbreeding, ...

A new mouse model provides insight into genetic neurological disorders The diverse characteristics of inherited nervous system diseases such as Charcot-Marie-Tooth and hereditary motor neuronopathy.

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time. The achievement, presented at the 25th ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a comprehensive set of innovative genetic tools and mouse lines, called iFlpMosaics, designed to enhance the ...

Boost for mouse genetic analysis 96% of mouse genome accessible to high-resolution single-cell analysis -- MADM technology expanded in new resource published in Cell Reports ...

Mosaic Mouse Technique Offers A Powerful New Tool To Study Diseases And Genetics Date: May 6, 2005 Source: Stanford University Summary: A powerful laboratory technique used by fruit fly ...