When quiescent neural stem cells in the fruit fly larval brain are activated, they can generate new neurons. In the photo, the nucleus of quiescent neural stem cells is labelled by a marker of ...

A brain enzyme activates dormant neural stem cells, revealing how defects in its gene could lead to neurodevelopmental disorders.

This image shows a postnatal neural stem cell (NSC) in the ventricular-subventricular zone. The majority of postnatal NSCs are maintained in a quiescent state, allowing for long-term maintenance.

A postnatal neural stem cell (NSC) in the ventricular-subventricular zone. The majority of postnatal NSCs are maintained in a quiescent state, allowing for long-term maintenance.

Researchers find that 'waves' of Hes1 and Ascl1 gene expression control the quiescent and active state of adult neural stem cells. Hes1 expression promotes quiescence and suppresses Ascl1, and ...

The vasculature is a prominent component of the subventricular zone neural stem cell niche. Although quiescent neural stem cells physically contact blood vessels at specialized endfeet, the ...

In various tissues, metabolic profiles of the stem cell niche and of the stem cells themselves play a critical role in determining whether the cells remain quiescent or transition to an active ...

Our goal was to create a new tool that could identify if an adult neural stem cell was quiescent and its different substates (dormant or resting quiescence), or if the cell is activated, entering ...

A study of the epigenetic enzyme Pr-set7/Set8 by researchers at Duke-NUS Medical School in Singapore has shown it to play a key role in stimulating neural stem cells (NSCs) from their quiescent state, ...

New Understanding of Neural Stem Cell Activation in Adult Brains New research has revealed important insights into the activation dynamics of neural stem cells.

Enzyme Plays Key Role in Waking Brain Stem Cells from Dormant State February 12, 2021 When quiescent neural stem cells in the fruit fly larval brain are activated, they can generate new neurons.