Tenofovir was detected in the cervicovaginal fluid samples of 7 of the 29 women (24%) assigned to tenofovir gel who acquired HSV-2 infection.

Tenofovir, one of the most effective and commonly prescribed antiretroviral medications for HIV/AIDS, is associated with a significant risk of kidney damage and chronic kidney disease that increases ...

A gel containing 1% tenofovir, used before and after sexual intercourse, has reduced new HIV infections by 39% and the risk for herpes simplex virus infections by 51% in high-risk women in Africa.

“Tenofovir use appeared to confer protection against more severe COVID-19 outcomes irrespective of HIV status,” the researchers concluded.

Besifovir is in phase 3 clinical trials, while tenofovir exalidex is in early development. Nucleoside/nucleotide analogues for hepatitis B can suppress viral replication during treatment, but they ...

Tenofovir + ddI has become a commonly prescribed regimen, but evidence is mounting that it may be problematic. Eugenia Negredo and colleagues previously reported that tenofovir combined with full ...

We conducted a randomized, placebo-controlled trial to assess daily treatment with oral tenofovir disoproxil fumarate (TDF), oral tenofovir–emtricitabine (TDF-FTC), or 1% tenofovir (TFV) vaginal ...

A topical gel with anti-HIV activity has been shown to be safe and well tolerated by HIV-positive and HIV-negative women. In a study published in the February 28th edition of AIDS investigators from ...

The use of oral tenofovir-based PrEP for HIV prevention in hepatitis B-endemic countries and in high-risk populations could “markedly decrease” the number of HIV and HBV coinfections ...

For most people, experts say, the two tenofovir-based drugs — the first known as T.D.F., the second called T.A.F. — offer roughly equal risks and benefits.