The rest of the top ten largest companies in Europe by market cap include ASML ( ASML ), SAP SE ( SAP ), Hermès International ( OTCPK:HESAY ), Roche Holding AG ( OTCQX:RHHBY ), Accenture plc ( ACN ), Nestlé S.A ( OTCPK:NSRGY ), AstraZeneca PLC ( AZN ), and Novartis AG ( NVS ).