A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “A case report of donor cell–derived ...

The CD34+CD38− cells, isolated from acute myeloid leukemia (AML), were shown to ... with the relative quiescence of stem cells, and chromosomal aberrations and mutations of leukemic cells.

Laboratory analyses showed that the patient who developed AML had significant chromosomal abnormalities and mutations in the RUNX1 and PTPN11 genes typically associated with the development of the ...

DNA Damage Can Last Unrepaired for Years, Changing Our View of Mutations Jan. 15 ... could have implications for the treatment of acute myeloid leukemia and ... How Breast Cancer Cells Survive ...

According to the American Cancer Society, rates of leukemia — particularly acute myeloid leukemia — are higher ... CLL develops when genetic mutations cause cells to replicate uncontrollably.

Genomic Interrogation of Secondary-Type Acute Myeloid Leukemia: Response and Outcomes to Contemporary Therapies,” published in the February 2025 issue of American Journal of Hematology by Senapati et ...

The root causes of most forms of Alzheimer's disease largely remain a mystery. Now, researchers have revealed a new piece of ...

In January 2025, Aptose announced the initiation of the TUSCANY trial and dosing in the first cohort of newly-diagnosed AML patients with the lowest starting dose (40 mg) of TUS as part of the ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

The race is on between Kura Oncology and Syndax Pharmaceuticals. On Wednesday, Kura and its partner Kyowa Kirin announced that their targeted treatment ziftomenib succeeded in a key study for ...

High-throughput techniques to analyze the AML genome in greater depth have revealed novel mutations with putative roles in leukemogenesis. The use of prognostic biomarkers has allowed for a more ...