STAG2 protein mutations and associated spatial alteration of DNA structure can contribute to development of leukemia
studied hundreds of patients with acute myeloid leukemia (AML). They discovered that specific mutations in the STAG2 protein ...
Too Old to Operate1d
Impact of Genomic and Clinical Ontogeny on AML Outcomes
Genomic Interrogation of Secondary-Type Acute Myeloid Leukemia: Response and Outcomes to Contemporary Therapies,” published in the February 2025 issue of American Journal of Hematology by Senapati et ...
Nature13d
Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells
The CD34+CD38− cells, isolated from acute myeloid leukemia (AML), were shown to ... with the relative quiescence of stem cells, and chromosomal aberrations and mutations of leukemic cells.
EurekAlert!6d
Rare case of donor cell-derived blood cancer discovered nine years after stem cell transplant
A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “A case report of donor cell–derived ...
pharmaphorum9d
bluebird seeks gene therapy trial restart after cancer scare
Laboratory analyses showed that the patient who developed AML had significant chromosomal abnormalities and mutations in the RUNX1 and PTPN11 genes typically associated with the development of the ...
Hosted on MSN9mon
What Is The Aggressive Form Of Blood Cancer Syria's First Lady Asma al-Assad Has Been Diagnosed With?
According to doctors, AML happens due to mutations in certain genes or chromosomes. There are several AML subtypes, all of which can affect your blood cell levels, but have different symptoms and ...
Medscape4y
Molecular Diagnosis of Leukemia
It is worth noting that gross chromosomal abnormalities can only be detected in a proportion of leukemia (e.g., in approximately 55% of AML). When metaphase cytogenetic analysis is applied to the ...