This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...

These cell lines were authenticated at ATCC before purchase by their ... The following antibodies were used: VLDLR (Proteintech, #19493-1), OCT4 (Abcam, #ab19857), SOX2 (Santa Cruz Biotechnology, ...

Primary antibodies included CTSL antibody (1:10000, Abcam Catalog No. ab200738), β-actin antibody ... MDA-MB-231 and MCF-7 breast cancer cell lines were cultured in an incubator containing 5% carbon ...

More than 13 years after its initial FDA approval, Pfizer’s blood cancer drug Adcetris has nabbed another regulatory green ...

Cell line development plays a pivotal role in the manufacturing of therapeutic proteins, vaccines and other biologics.

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Scientists have been working for decades to create synthetic cells that mimic key functions of biological cells. The challenge has been to make the artificial cells dynamic, responsive ...

A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Two studies by researchers at the University of Konstanz investigated ...