A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...

They are generated in living systems from acetyl-coA by the HMG-CoA reductase pathway. Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ ...

Through producing acetyl-CoA from acetate, ACSS2 epigenetically controls gene expression. However, whether and how ACSS2 regulates senescence remains unclear. Here, the authors link ACSS2 ...

Through the generated simulations, we have shown that KB concentration levels rise during prolonged starvation, and in consideration of glucose hypometabolism, MCT-induced intervention increases the ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Objective: Cognitive impairment is one of the core symptoms of schizophrenia, which is stable and lifelong. L-carnitine has been shown to improve cognitive function and decrease the rate of cognitive ...