Enzymes are the engines of life − machine learning tools could help scientists design new ones to tackle disease and climate change
Enzymes significantly speed up the chemical reactions that keep you alive. Researchers are using AI to create new ones to tackle modern challenges.
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How Neurotransmitters Work and What They Do
Neurotransmitters that act as neuromodulators include acetylcholine, dopamine, serotonin, histamine, and cannabinoids. Some neurotransmitters, such as acetylcholine and dopamine, can create both ...
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First successful clinical trial of VU319 brings Alzheimer's treatment one step closer
John Kuriyan, dean of basic sciences and University Distinguished Professor of Biochemistry and Chemistry ... The neurotransmitter acetylcholine is responsible for learning and memory, but ...
Nature17y
Neural stem cells, acetylcholine and Alzheimer's disease
In particular, the finding that acetylcholine-receptor antagonists have an antiproliferative effect on neural stem cells has important implications for the understanding and treatment of Alzheimer ...
EurekAlert!2y
Acetylcholine signal cascade during an aversive learning episode (IMAGE)
Upon aversive stimulus (electric foot shock), acetylcholine activates PAK kinase through the M1R-PKC cascade to facilitate synaptic plasticity. It also enhances PKC-mediated KCNQ2 phosphorylation ...