These function as "eat me" signals to the macrophages, which detect them via Fc receptors (FcR) embedded in their cell ...

caused distinct pathways to be activated that led the cells toward a less effective repair, as a response to the environment and external signals. Having identified a population of macrophages ...

The study shows that mitochondria do more than provide energy; they play an active role in modulating the immune response.

Resting macrophages are phagocytic, but macrophages activated by both intrinsic and extrinsic stimuli acquire a broad range of functions ranging from the release of reactive oxygen and nitrogen ...

Ashvattha Therapeutics (“Ashvattha”), a clinical-stage company advancing a new class of nanomedicine therapeutics that traverse tissue barriers to selectively target and reprogram activated cells in ...

Atherosclerosis risk is elevated in diabetic patients, but the underlying mechanism such as the involvement of macrophages remains unclear. Here, we investigated the underlying mechanism related to ...

Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular proteins, such as those from bacteria, in order to activate an ...

Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to macrophage-based therapies.