Researchers have pioneered a new catalytic transformation that converts epoxides into fluorinated oxetanes, a coveted but difficult-to-make class of drug molecules that escaped synthetic preparation ...

Researchers from the National University of Singapore (NUS) have pioneered a new catalytic transformation that converts ...

Small, polar rings and electron-withdrawing atoms are both well-loved motifs in medicinal chemistry. So oxetanes and fluorine atoms could be a match made in drug discovery heaven. Researchers devised ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. While performing a high-throughput screen (HTS) that identified ...

and oxidation reactions. Phase I enzymes relevant to psychotropics include the cytochrome P450 (CYP) family of enzymes, flavin-containing monooxygenases, esterases, epoxide hydrolases (EH), and ...

10 The great versatility of cardanol epoxide has boosted our interest in obtaining amphiphilic β-hydroxy sulfides through ring opening with thiols and subsequent oxidation of sulfides to sulfoxides ...

Smart citations by scite.ai include citation statements extracted from the full text of the citing article. The number of the statements may be higher than the number of citations provided by ACS ...

The rumbling was felt up and down the New England coast, and while most reactions were of the “Did you feel that??” variety, there were also plenty of clever takes from Greater Boston ...

Previous experimental studies have suggested that the force applied by the ball to the system accelerates the chemical reaction, but it is not well understood how macroscopic forces influence ...

Chemical reactions occur in a variety of situations with a wide range of different reaction types. Some chemical reactions occur extremely quickly, such as the explosion of a firework. Other chemical ...