Using a rat model of type-2 diabetes that expresses amyloid-forming human amylin in the pancreas (the HIP rat), we previously ... microvascular injury involve damage of the endothelial cell tight ...

The Trump administration’s cuts to university research grants will make America sicker and poorer in the long run.

Plasma insulin, C-peptide, glucagon, (total) amylin, gastric inhibitory peptide (GIP), and ... and increases circulating plasma TAG concentration. Exposure of pancreatic beta-cells to excess fatty ...

Symlin (pramlintide) is an amylin analog used in conjunction with insulin ... However, in some cases, two other medical procedures are used: islet cell transplantation and whole pancreas ...

The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...

Pancreatic cancer is fueled by connections to the nervous system. This is reported by scientists from the German Cancer ...

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders.

Pancreatic cancer (PC) is the worst prognosis cancer globally, with just 13% of patients who are diagnosed with PC surviving for 5 years or more after initial diagnosis. Early detection of PC is the ...

The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing ...

Their study, titled Intercellular TIMP-1-CD63 signalling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells, was based on laboratory experiments using ...