A review of recent trends and remaining challenges in bispecific antibody (bsAb) production has been published.

A PAT roadmap should address data analysis, aggregation, visualization, and the smart utility of those data for greater process understanding.

Continuous manufacturing (CM) has become a contentious topic in the modern pharmaceutical lexicon, driven by divergent ...

RIP constitutes the second enzyme, along with caspase-8, that is a direct downstream mediator of Fas ... by adding 1 μg/ml of cross-linking antibodies to Flag (M2, Sigma, St. Louis, MO).

The use of electrical impulses also speeds up the purification process, Ferrand-Drake del Castillo says, explaining that “instant millisecond switches reduce the cycle time and use of raw materials by ...

Such growth makes China an increasingly important player in the global biopharmaceutical industry, offering potential market ...

The SARS-CoV-2 pandemic interrupted much respiratory research. Respiratory clinical academics joined colleagues in providing clinical care, and global research efforts were directed to finding new ...

The novel nanobody-based HER2-targeted antibody, A9B5-Fc, binding to HER2-ECD I ... The nanobody’s expression and purification were performed as previously described (27). Briefly, the vectors were ...

This work presents a valuable exploration of AI-assisted protein engineering, particularly in designing a VHH antibody with enhanced resistance ... Our mutants have already been widely applied in the ...

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The purification system is the most intense of the bottles tested. It can filter out chemicals, pesticides, particles, heavy metals, bacteria and viruses. It also takes little to no prep or ...