The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

These mRNAs are unique in that they are not polyadenylated but have a stem–loop structure in their 3′ untranslated region. An early event in 3′ end formation of histone mRNAs is the binding of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. AAVPureMfg produces high-purity AAV vectors ...

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Department of Chemistry, University at Buffalo, The State University of New York, and the NYS Center of Excellence in Bioinformatics & Life Sciences, 657 Natural Sciences Complex, Buffalo, New York ...

The authors report how a previously published method, ReplicaDock, can be used to improve predictions from AlphaFold-multimer (AFm) for protein docking studies. The level of improvement is modest for ...

We report two patients in whom the detached stent was retrieved using alternative techniques—‘deploy and engage’ and ‘loop and snare’—as snare retrieval failed.

The parvovirus genome contains two open reading frames (ORFs) that encode the non-structural protein Rep and the capsid protein VP, which are further translated into functional proteins. Specifically, ...