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Visualization tool illuminates breast cancer cell migration, suggesting new treatment avenues
Cancer cell movement during metastasis is a dynamic process regulated by several different signals. However, the way cells ...
ascopubs.org4d
Phase II trial of lenvatinib (LEN) plus pembrolizumab (PEMBRO) for disease progression after PD-1/PD-L1 immune checkpoint inhibitor (ICI) in metastatic clear cell renal cell ...
FRACTION-RCC: Innovative, high-throughput assessment of nivolumab + ipilimumab for treatment-refractory advanced renal cell carcinoma (aRCC). Biomarker analyses from the phase III CheckMate 214 trial ...
Nature2d
Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis
Tissue morphogenesis requires the precise control of cell shape and cell dynamics. Cell shape is governed by cell mechanics, which explains how a set of intracellular and extracellular forces ...
ascopubs.org5d
Phase 1 study of AMG 119, a chimeric antigen receptor (CAR) T cell therapy targeting DLL3, in patients with relapsed/refractory small cell lung cancer (SCLC).
Phase 2 trial of first-line pembrolizumab with platinum doublet chemotherapy and radiotherapy in patients (pts) with unresectable, locally advanced stage III non–small-cell lung cancer (NSCLC): ...