Exciting news for Binding of Isaac fans! Edmund McMillen confirms "with certainty" that a future entry will eventually happen ...

Edmund McMillen, the creator of The Binding of Isaac, has commented on the possibility of a new game in the series arriving ...

Discover powerful treasures like Epic Fetus, Death's Touch, and Chaos Card in The Binding of Isaac: Rebirth. The randomized eight-level game offers tense challenges with 20 bosses to conquer and ...

Repentance+ Beta v1.9.7.9. Although it’s not as big as the previous ones, it still includes some changes which are worth ...

Ubiquitin-binding domains (UBDs) are modular elements that bind non-covalently to the protein modifier ubiquitin. Specific ubiquitin–UBD interactions are crucial for the regulation of multiple ...

A rare flower with a pungent odour that has been likened to decaying flesh, rotten eggs and sewage has bloomed in Australia - the third such flowering in recent months. The corpse flower ...

PHOENIX (AZFamily) — Isaac School District got official approval for a lease-back deal on Thursday from a neighboring school district to help them with their budget crisis, but the top question ...

Isaac Arnsdorf is a senior White House reporter. He joined The Post in 2022 to cover Republicans, the MAGA movement and the Trump campaign. He was previously an investigative reporter at ...

West Bromwich Albion have signed midfielder Isaac Price from Belgian club Standard Liege for an undisclosed fee. The club's first new recruit since the return to the club of boss Tony Mowbray ...

Isaac Newton changed the way we understand the Universe. Revered in his own lifetime, he discovered the laws of gravity and motion and invented calculus. He helped to shape our rational world view ...

Herzog: ‘I want to hear my neighbors say how much they object, regret, condemn and do not accept in any way the terrible tragedy of the terror attack of Oct. 7 ...