AIMp1 transcription measured by qPCR was not affected by E2, however ubiquitination of AIMp1 was increased by addition of E2 suggesting that HCV E2 targets AIMp1 for proteasomal degradation. Because ...
Extracellular vesicles (EVs), as cell-derived small vesicles, facilitate intercellular communication within the tumor microenvironment (TME) by transporting biomolecules. EVs from different sources ...
Other detailed experimental procedures and specific materials are described in online supplementary materials and methods, including patients, isolation of human articular cartilage chondrocytes, ...