After the administration of a single dose of the drug to this patient, the urine was examined for carbonic anhydrase inhibitor activity. Seventy-two per cent of the administered drug was recovered ...

A series of tight binding carbonic anhydrase (CA) activators was obtained by reaction ... CA I, II, and IV. Very good activity was detected against hCA I and bCA IV (h = human; b = bovine isozymes), ...

It is a potent enzyme inhibitor of carbonic anhydrase, and it impedes the activity at the choroid plexus reducing CSF secretion. A recent Cochrane systematic review identified two randomised control ...

Epilepsy is primarily treated symptomatically—that is, the majority of the available medications aim to suppress seizures ...

Epilepsy is primarily treated symptomatically - that is, the majority of the available medications aim to suppress seizures ...

SGLT-2 inhibitor use vs DPP-4 inhibitor use was associated with lower incidence of epilepsy among patients with type 2 diabetes.

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of ...

Carbonic anhydrases (CAs ... and the possibility of reversing this phenomenon by inhibiting the catalytic activity of the enzyme with a CA IX-selective and potent inhibitor.

More information: Sándor Beniczky et al, Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy, Epilepsia (2025). DOI: 10.1111/epi.18338 ...

A mechanism involving potassium channels in the brain that control brain cell activity could provide a new and fundamentally different way of treating depression symptoms in adults with major ...