Mitochondrial stress disrupts insulin production in diabetes, but reversing the damage may restore β-cell function.

Jumbo phages utilize a complex protein import system, with Imp1 as a key gatekeeper, to transport proteins into their ...

Most neuroscience research carried out up to date has primarily focused on neurons, the most renowned type of cell in the ...

Oxytocin receptor (Oxtr) signaling influences complex social behaviors in diverse species, including social monogamy in prairie voles. How Oxtr regulates specific components of social attachment ...

Scientists uncover how the nucleolus, a tiny structure within cells, may control aging and lifespan, opening new ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Mitochondria play a crucial role in cellular energy production, and their dysfunction has long been linked to metabolic ...

Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating ...

Mitochondrial damage is common in metabolic diseases like Diabetes, affecting insulin production and function in patients. Diabetics’ insulin-producing β-cells have abnormal mitochondria, impairing ...

"Our results demonstrate that the mitochondria can send signals to the nucleus and change the fate of ... saw that the same stress response was turned on. Both cell types were unable to mature and ...

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondria are essential for generating energy that fuels cells and helps them function.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...