Scientists have progressed from merely provoking an anti-cancer immune response to designing it ...

A groundbreaking immunotherapy is showing unprecedented success against one of the deadliest childhood brain cancers — ...

Despite hosting more oncology start-ups, Europe is lagging in the development of cancer technologies, losing the competitive ...

This sensitized other dendritic cells and macrophages in the tumor environment to topical imiquimod therapy, which inhibited the formation of new blood vessels via the cytokine IL12 leading to the ...

Oncolytic viruses (OVs) are viruses that infect and kill cancer cells while sparing healthy tissue, making them a promising therapeutic option in cancer ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of ...

These can be classified in to those directed against cytokines involved in cell proliferation, survival and differentiation (i.e., IL-2, IL-4, IL-9 and IL-12), and those linked to the inflammatory ...

One reason is the fact that much research related to ovarian cancer has focused on strategies combining chemotherapy with immunotherapies such as checkpoint inhibitors, due to the limitations ...

Immunotherapy. 2012;4(1):107-120 ... characterized by the production of different cytokines and associated with protective, nonprotective or regulatory responses to infection.

Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...

Cytokines are proteins ... Modelling the tumour immune microenvironment in vitro is a valuable tool to test immunotherapy efficiency but capturing its complexity is challenging.