Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older. The ...

Skoltech researchers have enlisted generative artificial intelligence to complete the missing data on the distances between ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

Harvard University researchers at the Broad Institute report that expansion in situ genome sequencing (ExIGS) linked nuclear ...

Chinese researchers have developed a technology that sheds light on how the three-dimensional (3D) organization of plant ...

We introduce MADna, a sequence-dependent coarse-grained model of double-stranded DNA (dsDNA), where each nucleotide is described by three beads localized at the sugar, at the base moiety, and at the ...

The productivity and accuracy of DNA methylation detection rely critically on the optimization of methodologies and the continuous refinements of related sequencing platforms. Here, we describe a ...

For most genomes that have been sequenced, researchers used short-read DNA sequencing technologies. These techniques work by first breaking genomes into millions of tiny segments, which can be ...

The authors advance this technique by integrating peptide ligation technology and nanobody-based antibody mimetics - cost-effective and scalable alternatives to conventional antibodies - into a ...