This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Anti-CD3 positive cells in epithelial and interstitial tissues ... of both workflows on the basis of a colon sample stained with DAPI and for FOXP3, CD25 and CD4.

Cell cycle re-entry of senescent breast cancer cells after CDK4/6 inhibition (CDK4/6i) constitutes a major source of disease ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...

A team led by the Institute for Bioengineering of Catalonia (IBEC) and the Hospital del Mar Research Institute has developed ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Achieved statistical significance on primary endpoint at Week 12 on mean change from baseline DAS-28 CRP across all rosnilimab doses vs.

The FDA has granted Fast Track designation to ADI-001 for the treatment of refractory systemic lupus erythematosus with extrarenal involvement.

Many cells in multicellular organisms are specialised. They have specific roles in the organism of which they are part. Their structure is adapted to their function. They are often grouped ...

The Micro Immune Response On chip (MIRO) allows tumours and their environment to be replicated in order to understand their ...

Feb. 10, 2025 — Evolution is traditionally associated with a process of increasing complexity and gaining new genes. However, the explosion of the genomic era shows that gene loss and ...