Activation of PPARα was found to enhance the intrinsic excitability of neurons in the dentate gyrus, suggesting that NPS signaling may be involved in the modulation of fear responses and anxiety ...

Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Rössle-Straße 10, 13125 Berlin, Germany ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

Here, we investigated the roles of DLK in hippocampal glutamatergic neurons using conditional knockout and induced overexpression mice. We found that dorsal CA1 and dentate gyrus neurons are ...

However, neurons that express IL-1R1 are not thought ... Among the brain regions identified as expressing nIL-1R1, the dentate gyrus (DG) was consistently highlighted, reaffirming its role as ...

Our findings confirm the presence of immature neurons in several regions of the cerebral cortex ... neuronal maturation has been already described in the PCX and the dentate gyrus of adult rats ...

A new study has identified a group of neurons that, when activated, can induce a hypometabolic state, akin to hibernation. The discovery could have far-reaching implications for conditions like ...

Mirror neurons received significant media attention in the 2000s and were painted by some scientists as the key to many of our advanced social abilities. However, many of the more significant ...

While the brain typically reaches a mature state of development in early adulthood, the internal processes that make and remake the brain—the birth of new neurons and death of old ones ...

This valuable study shows that a very slow (infraslow) oscillation occurs in voltage recordings from the dentate gyrus of the adult mouse. The authors suggest that it is related to sleep stage and ...

The body has billions of nerve cells Every person’s body contains billions of nerve cells (neurons). There are about 100 billion in the brain and 13.5 million in the spinal cord. The body’s ...