How the gut triggers lasting pain in common conditions
A global research collaboration has revealed how certain gut cells switch on pain signals, which can linger long after the ...
Frontiers1y
Astragaloside IV improves slow transit constipation by regulating gut microbiota and enterochromaffin cells
Purpose: Slow transit constipation (STC) is a common gastrointestinal disorder characterized by altered gut microbiota and reduced number of enterochromaffin cells (ECs). Astragaloside IV (AS-IV), a ...
Frontiers2y
Digital Spatial Profiling Reveals Functional Shift of Enterochromaffin Cell in Patients With Ulcerative Colitis
2012; Kobayashi et al., 2020). However, understanding of the pathology of UC remains inadequate. Enterochromaffin (EC) cells are a major component of the enteroendocrine system. Although they only ...
Nature11y
Overexpression of gastric leptin precedes adipocyte leptin during high-fat diet and is linked to 5HT-containing enterochromaffin cells
Enterochromaffin (EC) cells and expression of leptin, PAX4 (critical factor for EC specification), tryptophane hydroxylase-1 (TPH1, the peripheral rate-limiting enzyme for 5HT) and 5HT were ...