Mutation increases enzyme in mouse brains linked to schizophrenia behaviors
A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with ...
SMYD3 enzyme found to suppress antiviral immune response
Interferon regulatory factor 3 (IRF3) is a key transcription factor in the type I interferon signaling. Its activation must be tightly controlled to efficiently activate innate immunity while avoiding ...