How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA.

The Merrick laboratory seeks to identify all of the eukaryotic translation initiation factors and determine their sequential utilization in the initiation pathway. A secondary goal is to characterize ...

"As the central translation machinery that is essential for all life, the ribosome and the factors associated with ... IRESes have also been described in eukaryotic cells, which, unlike viruses ...