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Restricting SLC7A5-mediated Leucine uptake in T cells prevents acute GVHD and maintains GVT response
Limiting dietary L-Leu intake is a promising strategy to avoid SLC7A5-mediated allogenic T cell expansion and aGVHD while ...
May 23, 2025 — Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based ...
At its third attempt, Mesoblast has secured FDA approval for Ryoncil as a treatment for children with graft-versus-host disease, the first-ever approval for a mesenchymal stromal cell (MSC ...
Stem-cell research is the area of research that studies the properties of stem cells and their potential use in medicine. As stem cells are the source of all tissues, understanding their ...
The US regulator has approved Aucatzyl (obecabtagene autoleucel or obe-cel) for the treatment of adults with relapsed or refractory B-cell precursor ALL based on the results of the phase 2 FELIX ...
ST2L was originally investigated as a cell-surface marker for a subclass of T-cell leukocytes, the type II T-helper (Th2) cell. More recently, ST2L has been shown to participate in activation of ...
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BACKGROUND/AIMS Intestinal metaplasia (IM) is a common finding at the oesophagogastric junction, but the aetiopathogenesis of the different IM subtypes—that is, incomplete IM (specialised columnar ...
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