The novel PDE10A inhibitor CPL'36 offers a new mechanism of action and is both safe and effective for acute exacerbations of schizophrenia, new research suggests.

A quick fix for ED has been on the wish list of millions of men for decades — maybe even centuries. If the internet is any ...

Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many years of investigation ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Despite these advances, current synthetic strategies for DNA ...

Genetic knockdown of DHX9 results in strong reduction of proliferation and survival in CRC cells characterized as MSI-H/dMMR, but not in microsatellite stable (MSS) CRC cells with proficient MMR (pMMR ...

This study describes an improved adaptive sampling approach, multiple-walker Supervised Molecular Dynamics (mwSuMD), and its application to G protein-coupled receptors (GPCRs), which are the most ...

High-quality mechanistic and clinically relevant science to keep clinicians at the forefront of the latest advancements in the diagnosis and treatment of heart failure ...