† Department of Pediatrics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada ∥ Michael Cuccione Childhood Cancer Research Program, BC Children’s Hospital Research Institute, ...

The AMP-activated protein kinase (AMPK) system acts as a sensor of cellular energy status that is conserved in all eukaryotic cells. It is activated by increases in the cellular AMP:ATP ratio caused ...

The novel PDE10A inhibitor CPL'36 offers a new mechanism of action and is both safe and effective for acute exacerbations of schizophrenia, new research suggests.

Erectile dysfunction (ED) is a common condition affecting millions of men worldwide. It can impact self-confidence, relationships, and overall quality of life.

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In HFpEF mice and patients with HFpEF, increased musclin expression was accompanied by decreased cyclic guanosine monophosphate levels and PGC-1α expression in SkM, suggesting impaired NP signaling.