Stem cells can produce any other cell type, it is just a matter of telling them in the right way. From a biological ...

Led by Lars Velten, PhD, group leader at the CRG, the study designed enhancers with specificity to user-defined combinations of hematopoietic ... In blood stem cell differentiation, single-cell ...

More information: Luis Galan Palma et al, An unbiased genomewide screen uncovers 7 genes that drive hematopoietic stem cell fate from mouse embryonic stem cells, Blood Journal (2025). DOI: 10.1182 ...

As of 2024, approximately 167K individuals in the US were diagnosed with essential thrombocythemia, with about 75% of these ...

The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application (NDA) for ziftomenib as a treatment for adult patients with relapsed or refractory (R/R) acute myeloid ...

CR/CRh rate of 23% in pivotal Ph 2 cohort of R/R NPM1-m AML patients – – Consistent efficacy with comparable CR/CRh rates and clinically meaningful MRD-negative responses ...

In this single-arm trial, the median overall survival (OS) observed was 4.0 months (95% CI: 2.5-7.2) among all 64 adults in the primary efficacy analysis based on the Kaplan-Meier estimate. The median ...

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using ...