Most solid human tumours contain regions of acute and chronic hypoxia or anoxia that can herald a negative clinical prognosis for the cancer patient owing to local resistance and systemic metastases.
When they compared the genes in the hypoxia-response signature of normal cells to that of different cancer cells, they found that they were able to classify different tumors by their hypoxia response.
A collaborative study published on January 21 in Nature Communications presents a novel strategy to improve the effectiveness ...
Gilead Sciences has defied analysts’ expectations by passing on its chance to license Arcus Biosciences’ potential rival to Merck & Co.’s kidney cancer drug Welireg.
On Tuesday, the European Commission (EC) conditionally approved Merck & Co Inc’s (NYSE:MRK) Welireg (belzutifan), an oral ...
Casdatifan targets a transcription factor that binds with other proteins to switch off the body’s anti-inflammatory ...
This interview has been edited for length and clarity, but not his warning: “Hypoxia can be dangerous, and I can’t emphasize that enough. Hypoxia in the extreme can be very detrimental, ...
A collaborative study, published on January 21 on Nature Communications, presents a novel strategy to improve the ...
Among adults with relapsed or refractory indolent B-cell non-Hodgkin lymphoma, the phase 2 TRANSCEND FL trial met its primary ...
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