This influx of calcium at the contact site attracts and activates a kinase called CaMKII, a protein known to be important in ...

New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances.

Developed by Northwestern Engineering’s Igor Efimov and George Washington University’s Luyao Lu, the implantable device uses ...

The IP3/PKC signaling cascade is of paramount importance in the mechanism of calcium signaling and the preservation of neuronic integrity. The combined actions of these pathways play a significant ...

2:19 Ontario election needed because of Trump presidency, Ford claims Moments after U.S. President Donald Trump revealed his intention to apply steep tariffs to Canadian exports, Ontario Premier ...

Receptors coupled to G alpha q activate the IP3 calcium pathway through the alpha subunit ... overload via microgravity induced pressure changes that upregulate GPCR-calcium signaling. In T ...

These disruptions in calcium signaling affect rotavirus disease severity, providing new insights into how NSP4's function influences rotavirus virulence. The findings suggest that manipulating ...

In a significant boost to rail safety, Indian Railways has successfully upgraded its signalling system at Shakurbasti in New Delhi, replacing one of the country's oldest mechanical interlocked yards.

Studies by Jeffrey Klomp et al. 6 and Jennifer Klomp et al. 7 refine our understanding of the signaling effects of oncogenic KRAS. The studies suggest that mutant KRAS signals predominantly ...

A zero calcium score with high cholesterol may mean a person is at a lower risk of coronary heart disease. It means imaging does not show a buildup of calcified plaque in the heart’s blood vessels.

Notably, pharmacological inhibition of PDE9A via Bay 73-6691 or virus-mediated CHIP expression restored the balance of cGMP/cAMP signalling. These interventions protect against cerebellar ...