SCIENTISTS have discovered a "switch" that they say reverses cancer cells in a major development for finding a cure to the disease. Researchers in South Korea said they were able to revert ...

Levels of proliferation and immunoglobulin class switching to IgG and IgE produced by human B cells were determined, before and up to 10 days after stimulation, by using flow cytometry with mAbs as ...

cch.aphp.fr Objectives Pulmonary arterial hypertension (PAH) is characterised by remodelling of pulmonary arteries with enhanced vascular smooth muscle cell (VSMC ... scleroderma-associated PAH and ...

B-cell prolymphocytic leukemia (B-PLL) is a rare, aggressive type of leukemia that progresses rapidly. People with B-PLL typically have a less favorable outlook. However, new targeted treatments ...

Previous studies have shown they may interact with our hormones, or enter our cells and disrupt our DNA ... which could cause prolonged obstructions to blood flow in the brain.

Patient & methods: As part of routine medical care, the author monitored total and IgG subclass levels ... After being switched to daily SCIg therapy, the headaches stopped, and her annual ...

We study the role of T cells in mBC responses, using CD40L stimulation and autologous T-B co-cultures. Our results showed that increased CD40L levels led to a selective increased proliferation of IgM+ ...

Non-Hodgkin lymphoma (NHL) is generally divided into 2 main types, based on whether it starts in B lymphocytes (B cells) or T lymphocytes (T cells). There are many different types of B-cell lymphomas.

Here we present a new method for the metabolomic analysis of rare stem cell and cancer cell populations isolated by flow cytometry. We have increased the number of metabolites we can detect in 10,000 ...

Of the five classes of antibodies produced by B cells in mammals, IgG is the major class of antibodies in the blood. IgG activates complement, and binds Fc-receptors (FcRs) on macrophages and ...

B lymphocytes use B cell receptors (BCRs) to sense the physical features ... In contrast, the activation of isotype-switched IgG- or IgE-BCR only requires a low threshold of less than 12 pN, providing ...