Bristol Myers Squibb Co. has synthesized proteolysis targeting chimera (PROTAC) compounds comprising a cereblon (CRBN) E3 ubiquitin ligase-binding moiety coupled to a DNA-binding protein Ikaros (IKZF1 ...
This valuable study presents a screening pipeline (SPICE) for detecting DNA motif spacing preferences between TF partners. SPICE predicts previously known composite elements, but experiments to ...
Caitlyn Perry receives funding from the Australian Research Council. The common fruit fly (Drosophila melanogaster), more correctly called the vinegar fly, is a frequent visitor to ripe fruit in ...
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