Nucleic acids have become important diagnostic markers for many diseases, enabled by breakthroughs in synthesis and sequencing ... in the characterization of inhibitors against RNA MTases.

Davison, A. N., Biochim. Biophys. Acta, 19, 131 (1956).

Affinity Technologies, Inc. , a biotechnology company advancing noninvasive diagnostics and targeted therapeutics for cancer, today announced the U.S. Patent and Trademark Office (USPTO) has issued a ...

Lepodisiran, a long-duration small interfering RNA targeting lipoprotein(a) synthesis, reduced serum concentrations of ...

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

a liver-targeted fatty acid synthase (FASN) inhibitor being investigated for the treatment of metabolic dysfunction-associated steatohepatitis (MASH). BJT-188 demonstrated potent FASN inhibition ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

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At Booth #3255, Tsingke presented its comprehensive synthesis and expression service portfolio , offering essential support from early-stage discovery to preclinical development. Our platform drew ...

GSK has reported positive outcomes from the randomised Phase III GLISTEN trial of the targeted inhibitor of ileal bile acid transporter (IBAT), linerixibat. The therapy aims to treat adults with ...

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