Verastem Oncology , a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced multiple oral and poster presentations, ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and communication between the gut microbiota and the nervous system.

This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...

Melbourne-based scientists have, for the first time, discovered how to "switch off" a molecule which is one of the top ...

Image supplied by WEHI. Calmodulin binds to PSKH1 (in grey) to 'switch on' PSKH1 activity. Reticulocalbin binds to PSKH1 to 'switch off' PSKH1 ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...

Nurix Therapeutics, Inc. stock slid 40% after promising NX-5948 results in CLL. NX-5948 shows efficacy in heavily pre-treated ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Five-year data from the POETYK PSO long-term extension trial confirm the sustained efficacy and safety of Sotyktu ...

Protein phosphorylation is a cornerstone of cellular communication, orchestrating rapid and precise responses to ...