On immunohistochemistry (IHC), these tumour cells were positive for pan-Cytokeratin, negative for Leucocyte common antigen (LCA) and CD30. So, the final diagnosis was given as bone marrow involvement ...

Brain metastases are rare and poorly understood complications of ... multiple hepatic lesions measuring up to 4.1 cm and multiple aortocaval lymph nodes. Laboratory results were notable for ...

During a Case-Based Roundtable event, Laura Huppert, MD, discussed data and considerations around using T-DXd in breast ...

negative nodes II Tumor of any size with adjacent spread (1/3 lower urethra, 1/3 lower vagina, anus), negative nodes IIIA Tumor of any size with positive inguino ...

Taken together, the concept of the pre-metastatic niche also holds true in prostate cancer lymph node metastasis. Identifying key pathways of niche communication may have significant implications for ...

Metastatic breast cancer affects people in many ways. The symptoms experienced by each person will vary based on the parts of the body that are affected. Some symptoms are a result of the cancer, and ...

Computed tomography (CT) of the neck revealed an enormous nasopharyngeal mass extending into the right oropharyngeal, masticator, carotid, prevertebral, and paravertebral space, with multiple ...

Numerous studies have investigated the molecular mechanisms and signalling pathways underlying cancer metastasis, as there is still no ... as well as common cancer-related markers (e.g. cytokeratin or ...

Colorectal cancer (CRC) is a highly heterogeneous malignant disease that can metastasise to lymph node, liver, lung, bone and ovary. Heterogeneity in CRC primary tumour leads to organ-specific ...

The heterogeneity of brain metastases highlights the differences from their primary source of origin and contributes to therapeutic resistance. Before colonising the brain, tumour cells acquire ...