Abstract: We aim to apply protein sensors to rapid intraoperative diagnosis of lymph node metastasis. In the present study, cytokeratin, which is a biomarker of lymph node metastasis, was bound to ...

On immunohistochemistry (IHC), these tumour cells were positive for pan-Cytokeratin, negative for Leucocyte common antigen (LCA) and CD30. So, the final diagnosis was given as bone marrow involvement ...

The majority of documented extracranial metastases involve the liver, lymph nodes, thorax, spleen ... Additionally, the tumor cells were negative for cytokeratin and thyroid transcription factor-1 ...

Tumor location, tumor size, and T stage associated with patients with rectal cancer who have inferior mesenteric artery lymph node metastases. In patients with rectal cancer, there was an ...

Docetaxel administered through a novel lymphatic drug delivery system (LDDS) improved treatment outcomes for lymph node metastasis. Biomedicine & Pharmacotherapy , 2024; 171: 116085 DOI: 10.1016/j ...

To test this hypothesis, Kodama and his team administered the treatment to a preclinical model of a metastatic lymph node mouse model. Their findings confirmed superior therapeutic outcomes ...

Caecal cancer and ascending colon cancer had slower rates of metastasis to main nodes compared with transverse colon cancer. Routine prophylactic extended lymphadenectomy for the superior ...

Currently, detection of lymph node metastasis of thyroid cancer during surgery is limited and time-consuming. Elevated levels of Cyfra 21-1, the proteolytic portion of cytokeratin, are associated with ...

Results: The metastatic rate of the LN14v lymph node was 15.8% ... Immunohistochemical staining for cytokeratin nodes CK8/18 to evaluate micrometastases has been reported in other fields (16). This ...

9 In the SLNB group, SLN detection and tumor resection were performed; patients with metastasis-positive nodes, proven by frozen section diagnosis, underwent therapeutic ND as a one-stage procedure.

Metastases can form in locoregional lymph nodes draining the primary tumor-a form of progression that portends a worse prognosis but can still be curable-or they can develop in distant organs.

What’s concerning is that those patients can ultimately develop visceral disease, not just lymph node disease. There’s a group of patients who first develop metastatic disease in lymph ...