Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...

The 35-year-old left-hander always flashes back to losing his dad to colon cancer at the start of his sophomore year at his ...

New York Yankees bullpen pitcher Tim Hill is 35 years old, and he re-signed with the team in the offseason. Hill is a person ...

The researchers performed targeted exome sequencing—a gene sequencing technique used ... and mismatch repair pathway genes MSH2 and MSH6, were frequent and significantly associated with a ...

The team is optimizing the cancer genome analysis system to integrate it into CRC diagnosis and tailor treatments based on ...

Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer ...

From 95 Lynch syndrome families, we selected all carriers of a germline mutation in the MSH2, MLH1 or MSH6 gene, who had been seen and registered at the Department of Human Genetics of the Radboud ...

We assessed mutational landscapes, tumor mutation burden (TMB), chromosomal instability scores (CIS), and gene expression using broad-panel ... enrichment of mutations in genes like KRAS, MSH2, MSH6, ...