Pinpointing the precise culprits behind harmful biological processes—such as excessive scarring (fibrosis) in organs like the ...

Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for ...

Researchers at Tel Aviv University's Gray Faculty of Medical & Health Sciences conducted a series of experiments using ...

The Cocoon® (from Lonza) is a functionally closed, sterile, efficient manufacturing platform, which combined with our ...

Macrophages, key players in the immune system ... This review summarizes how M-EVs influence tumor cell behavior, their mechanisms of action, and the challenges related to specificity, isolation, and ...

Background: It has been suggested that defective handling of apoptotic cells by macrophages plays a key role in the development of systemic lupus erythematosus (SLE). The relative contribution of ...

Scientists at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena discovered a previously unknown function of immune cells in the bone marrow. Embryonic macrophages - specialized ...

We show that interactions involving endothelial cells and macrophages/monocytes in the intima, where the ECM (extracellular matrix) microenvironment contains reduced TGFβ signaling, contribute to the ...

Lineage Cell Therapeutics remains focused on advancing OpRegen and OPC1, with a recent manufacturing achievement supporting broader partnering opportunities and potential expansion beyond current ...

He emphasized, “OpRegen has shown evidence of both anatomical and functional benefits lasting for up to two years and from a one-time surgical delivery of RPE cells to the subretinal space.” ...